There are 3 new caps - back row Mike Williams, prop Nathan Catt and back Alex Lozowski - whilst James Haskell, Maro Itoje, Anthony Watson, Jack Clifford and Jack Nowell all return after missing the November internationals through injury.
England are without a number of players through injury, including the Vunipola borthers, Mako and Billy, as well as former captain Chris Robshaw.
EddieJones has also added visual awareness coach Dr Sherylle Calder to his team of backroom staff. Dr Calder worked with the squad under Sir Clive Woodward and joins on a consultancy basis.
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